Post:Sara (Cameron Diaz) and Brian Fitzgerald (Jason Patric) have just been informed that their young daughter Kate (Sofia Vassilieva) has leukemia, and that she only has a few years to live. The doctor suggests to the parents that they try an unorthodox medical procedure of producing another child in a test-tube that would be a perfect match as a donor for Kate. Sara will try anything to save Kate, and they have a new baby Anna (Abigail Breslin) to be used as a donor for Kate. The first thing they use is blood from the umbilical cord for Kate. As years go on, the doctors must take bone marrow from Anna to give to Kate. At age 11, the next thing Anna must give to her sister is a kidney. Anna has had enough of all of these medical procedures, and she decides to sue her parents for medical emancipation and the right to decide how her body will be used. The whole family is being torn apart by Anna's decision because everyone knows what will happen to Kate if she doesn't get a new kidney. Anna will hire a maverick lawyer, Campbell Alexander (Alec Baldwin), who would look only onto Anna's interest, and nobody else's. Anna has paid a small initial fee with the money she obtained at a pawn shop. The judge orders Anna's parents not to pressure her at home anymore. Sara is the one who can't take that anymore, and she doesn't understand Anna at all. The judgement goes on, and everybody has to take sides one way or another. Later on, the audience learns that the idea about emancipation was not Anna's, in fact it was Kate, the always-sick one, who asked her to put a stop to her endless suffering.
Conceived by means of in vitro fertilization, Anna Fitzgerald (Abigail Breslin) was brought into the world to be a genetic match for her older sister, Kate (Sofia Vassilieva), who suffers from acute promyelocytic leukemia. Because of her sister's dependency on her, Anna is unable to live the life she wants; in and out of the hospital constantly, she cannot take part in extracurricular activities such as cheerleading or soccer. When Kate turns 13 she goes into renal failure. Knowing that she will have to donate one of her kidneys to her sister, Anna sues her parents for medical emancipation and the rights to her own body. Attorney Campbell Alexander (Alec Baldwin) agrees to work for Anna pro bono. The film is interlaced with flashbacks that detail the strong relationship between Kate and Anna, as well as how Kate's illness has affected her siblings' lives. Before the result of the case is known, it is revealed that Kate had asked Anna to file for medical emancipation. Believing that she would not survive the surgery, Kate wants to die. Anna wins the case, and due to her sister's wishes does not donate her kidney. Kate later dies at the hospital. The family moves on with their lives, being changed by Kate's death, but every year on Kate's birthday they go to Montana, which was her favorite place in the world.
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